: Oral route has always been preferred and most convenient route for drug administration. The major problem associated with oral route of drug administration is low bioavailability, which is due to poor aqueous solubility of drug entity. Approximately 35-40% of new drug entities exhibit poor aqueous solubility and present a major challenge to modern drug delivery system, because of their low bioavailability. For the improvement of bio-availability of drugs with such properties requires various pharmaceutical strategies including solid dispersions, cyclodextrines complex formation, and co-precipitation. Recently self emulsifying drug delivery system has gained more attention due to enhanced oral bio-availability and reduction in drug dose.\Self-Emulsifying Drug Delivery System is isotropic mixture of oil, surfactant, solvent, and co solvent. The principal characteristic of these systems is their ability to form fine oil-in-water emulsions or micro-emulsions upon mild agitation following dilution by an aqueous phase.
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